Which Is The Best Way To Get Traffic To Your Website: Search Engine Marketing (SEM) or Search Engine Optimization (SEO)?
What every CEO and entrepreneur wants is a blueprint to get their website on page number one of Google search results and that requires Search Engine Marketing (SEM), Search Engine Optimization (SEO) and a little bit of good luck. This article describes SEM and SEO and defines their role in developing a winning blueprint for internet success. It discusses the pros and cons of each.
Wikipedia defines internet marketing this way,"... it ties together creative and technical aspects of the Internet: design, development, advertising, and sales." SEM and SEO are a part of a total Internet marketing campaign that works to improve the search engine visibility of your webpage in search engine results.
SEM is an important part of promoting your business online and because ROI is important, businesses should use analytical software to track visitors, collect data to help improve their site for their visitors and increase conversion rates. SEM is paid internet advertising. That is, you have to pay the search engine (the publisher of the ad) to advertise your website or product/service.
The most effective advertising channel in the world is pay-per-click advertising. This advertising channel can help millions of internet users find your product and you only need to pay when they click on your ad: Google AdWords is an example of a pay-per-click provider.
SEM is a very target specific marketing method. A qualified SEM consultant can develop your digital marketing plan so you get a cost-effective, low-risk solution, giving you the freedom to defy the limitations and avoid the costs and risks of traditional marketing techniques. It involves strategically using search engines to promote a company's products and services.
SEM involves a combination of free website submissions, forum marketing, blogging, article submissions, paid search engine listings and a host of other marketing methods - some paid, some free. It is an umbrella term combining SEO with paid methods of marketing such as PPC campaigns and any paid for appearances or inclusions on the internet.
Paid advertisements should still be optimized for top placement amongst the results. And, although organic results will get more attention from visitors, the value of having your name right up there at the top of results from SEM should never be dismissed. Paid Inclusion is often used for time-sensitive websites which require frequent updates, or to keep the search engine index of a high standard.
SEO; on the other hand is a fickle process that changes from search engine to search engine. There is no guaranteed formula as to the success of your SEO, nor are there any fast and hard rules that anyone can follow. SEO might be better described as "website optimization". SEO is the art of creating a website that waves its arms in the search engines face (Google, Yahoo, MSN ...) and says, "Here I AM!" It is a dynamic part of your online marketing mix and should not be ignored or underestimated as a lead generator. SEO is hard work, research and relevancy.
SEO is a longer term process, especially for brand new sites, and can take anywhere from 6 to 12 months to achieve a top ranking. The difference between starting to implement SEO today and starting to implement SEO in 12 months could be disastrous, especially if your competitors get on the bandwagon before you do. SEO is a fluid process with rankings now changing on a daily basis. SEO also works well in combination with other SEM disciplines such as traffic analytics. SEM, on the other hand, is a part of even larger entity called Internet Marketing and operates on an effective but rather narrow platform which focuses only on search engines as its marketing delivery ground.
SEM is easier to set-up and is more flexible than SEO as it can be turned on and off with ease. SEO is a long term strategy and not one suited to time critical traffic generation. If you seek traffic that can be turned on and off with little more than your say so then perhaps it is time to consider other options such as Pay per Click marketing.
SEM is an extremely cost highly accountable and effective form of advertising. It delivers pre-qualified users direct to your website and all activity can be tracked through to customer acquisition. SEM is one of the only types of online advertising that is displayed to potential customers "on demand". Customers search actively for a specific term or phrase and expect relevant results to be returned. SEM is a process which takes time and patience. The next step is to create a schedule of monthly efforts.
SEM is a fantastic way to drive traffic to your website, and just because it's paid doesn't mean it has to be expensive. Google AdWords is a popular form of SEM, used by large and small businesses alike.
SEO traffic converts significantly higher than SEM traffic as web users tend to trust organic search results more than paid search results and thus convert at a higher rate. SEO also works well in combination with other SEM disciplines such as traffic analytics.
SEO is about maximizing your search engine positioning. You can Do-it-yourself or engage a search engine consultant to do the work for you.
When your websites listing is clicked, SEO is free to perform and renders no cost. Other benefits include larger listings in the search results and the ability to rank for large amount of long tail keywords. SEO is about maximizing your search engine positioning.
What every CEO and entrepreneur wants is a blueprint to get their website on page number one of Google search results and that requires Search Engine Marketing (SEM), Search Engine Optimization (SEO) and a little bit of good luck. SEO; on the other hand is a fickle process that changes from search engine to search engine. SEM, on the other hand, is a part of even larger entity called Internet Marketing and operates on an effective but rather narrow platform which focuses only on search engines as its marketing delivery check here ground.
SEO is about maximizing your search engine positioning. SEO is about maximizing your search engine positioning.
If you have a lot of junk in your garage, backyard, basement, office, deck, home, and attic, you may want to consider hiring the services of a junk removal company. Waste removal companies can remove your old furniture, belongings, old appliances, computers, televisions, tires, and almost anything else. They can also remove wood, debris, and fencing from your yard. Such companies do not usually remove hazardous materials or items. Junk removal companies specialize in removing unwanted junk and materials from apartments, homes, construction companies, and commercial businesses.
If you hire a trash removal company, you will not have to bring the waste to the curb. They will load the junk into their trucks and clean up afterwards.
Most junk removal companies take their jobs seriously and they can help you reduce the clutter in your home for a fair price. They will also make sure your trash is disposed properly and in an eco-friendly manner.
When their houses have been foreclosed and others use them when they need to remove stuff after a renovation or restoration, many people use junk removal companies. Additionally, many people use these companies when they need to get rid of furniture and over-sized items, and some people use them to clear fire damage.
Make sure you choose a reliable junk removal company. Make sure the removal specialists are licensed, bonded, and insured before they start working in your home. Do you know that if an employee gets injured on your property, you may be liable for a personal injury lawsuit? Accidents happen every day, so make sure the company is insured. A reliable contractor will be happy to show you proof of their liability insurance. website Removing trash is not an easy task and workers need to be in excellent shape. Injuries can happy at any moment. Protective clothing, footwear, and eye protection is also very important.
Junk removal companies usually have large vehicles so that their workers can get the job done quickly. Most junk removal companies use enormous trucks and trailers.
The best junk removal companies will respond to your needs quickly. There are many professional., helpful, and friendly waste removal companies around.
Waste removal companies will save you time and clear out your junk, so that you can go to work and take care of important things. They can help if you're demolishing something or need to clear unwanted items. They will get the job done quickly so that you can focus on work and your family.
Junk removal service companies are affordable even if you are on a strict budget. By doing research and checking a professionals' credentials and references, you will avoid many problems, save time, and feel good knowing that you have found a reliable company for your junk removal needs.
A junk removal company can help you remove heavy items, trash, toys, electronics and anything else you want to get rid of. They are there when you need their help and they will remove your junk as quickly as possible.
If you have a lot of junk in your garage, backyard, basement, office, home, deck, and attic, you may want to consider hiring the services of a junk removal company. Junk removal companies specialize in removing unwanted junk and materials from apartments, homes, construction companies, and commercial businesses.
The best junk removal companies will respond to your needs quickly. By doing research and checking a professionals' references and credentials, you will avoid many problems, save time, and feel good knowing that you have found a reliable company for your junk removal needs.
A junk removal company can help you remove heavy items, trash, toys, electronics and anything else you want to get rid of.
In most cities across the country, there are only a handful of top-tier restaurants. In Las Vegas, however, there are over 300 amazing restaurants on a single, 3-mile-long street. This makes it seem like you can show up to Vegas with your group and book a group or private dining room with little or no notice.
While there are certain cases where this is true, here is a guide to know when you should start booking your venues.
When do I not need to worry about booking far in advance?
There are certain times of the year that are slower in Las Vegas and many restaurants will have availability the week of your reservation. Having said that, when a large convention or music festival comes to Las Vegas, it can be difficult to find a good reservation even during the slow months.
Make sure you still plan early even if it is during the slow months. There is an average of 700,000 visitors on the Strip every week, so even during the slow months, it may be difficult to find the perfect group dining experience.
When are the busiest times on the Strip?
The busiest times on the Las Vegas Strip are during large conventions, holiday weekends and major sporting events. If you are coming to town during one of these weekends, make sure to start planning your event at least 4 months in advance. You can find a calendar of all of the largest conventions here: http://www.vegasmeansbusiness.com/planning-tools/convention-calendar/
The biggest holidays in Las Vegas are New Years Eve, Memorial Day, Labor Day and Halloween. The largest sporting festivals and events are PBR (Professional Bull Riders), NFR (National Finals of Rodeo), Electric Daisy Carnival, NASCAR, NBA All-Star game, major boxing events and more. During any of these weekends, restaurant reservations for groups can be difficult.
Certain casinos and parts of the Strip are busier than others.
In most of the large casinos, there are restaurants in high-traffic areas right on the casino floor, and most of these restaurants take advance reservations. If you are hoping to book a restaurant at the hotel where a visit VegasPrivateDining.com convention is taking place, keep in mind that the private dining rooms will be booked 4-6 months in advance, and semi-private group dining will be reserved shortly afterward.
There are weekends where the city is FULL. What should I do then?
If you simply can not find a space, there are companies that are local that can help, for example Vegas Private Dining, and most of the large casinos have group concierges that can usually find a space. Start with the resort where you are staying. If you have rooms reserved already, the group concierge will be more than happy to help.
This makes it seem like you can show up to Vegas with your group and book a group or private dining room with little or no notice.
During any of these weekends, restaurant reservations for groups can be difficult.
If you are hoping to book a restaurant at the hotel where a convention is taking place, keep in mind that the private dining rooms will be booked 4-6 months in advance, and semi-private group dining will be reserved shortly afterward.
If you simply can not find a space, there are companies that are local that can help, for example Vegas Private Dining, and most of the large casinos have group concierges that can usually find a space. If you have rooms reserved already, the group concierge will be more than happy to help.
The cost of today's average wedding has gotten so high, you might
think that the application of the word "budget" doesn't apply.
Of course you 'd be wrong.
Whether you're spending $3,000 (far below average, even in the
least expensive areas of the U.S., but I know several people
who've done it quite successfully) or you're spending $30,000.
( only a bit about the average cost of a wedding today, so average.
means plenty of people spend more), you still need a budget.
A budget isn't necessarily an attempt to spend less. It's a plan.
for where you'll spend the money you do spend, regardless of the.
I hope you're among the lucky few who can afford to spare no.
When planning the wedding of your dreams, expense. On the other.
hand, I know some fairly wealthy people, and I don't know anyone.
who didn't angst to a certain extent over the cost of their.
Most people simply can't afford or just would rather not to empty.
their savings and run up their credit for their wedding.
Weddings have this somewhat scary habit of being rapidly followed.
by even MORE expensive things to spend your hard-earned money on,.
more permanent things, like buying a house and having a baby (or.
Trickier still is the fact that many brides (the traditional.
planners of weddings) are marrying a bit later in life, when.
they're well ensconced in a career and don't have their weekdays.
free for interviewing wedding vendors and sampling cake.
Do Wedding Planners Cost or Save?
Of course professional wedding planners have to be paid, so in.
that way they obviously cost you. However an argument can be.
made (and is made, both by wedding planners themselves and by.
brides who've been happy with their professional planners) that.
having a professional wedding planner can save you money in other.
areas. An experienced wedding planner is involved in several.
weddings each year. This means that they'll have ongoing.
relationships with certain wedding vendors, and it behooves those.
vendors to cut the wedding planner a break on prices, so that.
she'll continue to use their services at all of the weddings.
she's involved with.
- Aside -.
Not that it affects your budget, but it also behooves wedding.
vendors to keep wedding planners happy with the service the.
vendor provides. As an individual, you're not likely to see.
these vendors again after you finish your wedding (at least not.
for a good long while, preferably not ever). A wedding planner,.
on the other hand, will see these vendors again and again; she's.
a repeat customer for them.
Vendors will, of course, value a repeat customer more than a one.
- time customer. They will convey this value with financial breaks.
and extra-good service. If push comes to shove, they may convey.
it by giving a wedding planner something (such as service on a.
popular date or that includes a hand-to-find item) that they have.
to take away from an individual bride. I know a bride who was.
promised a wedding venue for a specific date and then a week.
later the venue canceled on her, because they had a "repeat.
customer" who wanted that date and was willing to pay extra. My.
friend was not given the opportunity to pay extra or to outbid.
the repeat customer. She just lost the date.
- Aside -.
, if you find a wedding planner with a great reputation (with both.
brides and local vendors), you may get the best of everything: A.
wedding planner who can easily get you top-notch vendors and.
negotiate powerful bargains.
Even with a terrific wedding planner in your employ, you should.
still do your own research and talk to your planner with a strict.
budget in mind. If the planner can't control costs.
adequately, it's always your responsibility to offer cost-saving.
ideas of your own. , if your wedding planner doesn't stick to your.
budget, then she's the one who did a poor job, but it's still you.
who are out the money. The extra cost doesn't come out of the.
Still, no wedding planner is likely to save you more than she.
charges you. Hiring a wedding planner will result in higher.
financial wedding costs for you. The area in which an excellent.
planner will certainly save you, however, is in time. You'll.
need to invest far fewer hours toward organizing and ensuring the.
details of your wedding if you hire a wedding planner than if you.
The question for you to answer is whether you have more time or.
more money to invest in your wedding. Only you can answer that.
What's The Cost.
Wedding planners can charge you in any of three ways:.
oA percentage of the total cost of your wedding.
oAn hourly charge.
oA flat fee per specific services.
Although it's the least common, I recommend looking for vendors.
who use the last of those options. The problem with the.
percentage charge is that it creates an incredible conflict of.
interest for the planner. In essence, the more your wedding.
costs you, the more the planner gets paid. That's the colorado wedding planner opposite.
of how it should work, in my opinion! Most planners are ethical,.
and they die and live by recommendations, so they're unlikely to.
triple your expenses just to increase their cut, but at some.
level of consciousness, it's just not encouraging them to watch.
every penny in the way that I, personally, would like. If you're.
working with a planner who charges a percentage (15% is typical),.
talk about paying them a percentage of your budgeted wedding.
costs (rather than actual costs), plus a percentage of any amount.
they can come in under budget. Essentially offer them a bonus.
for coming in under budget. This will somewhat offset the innate.
conflict of interest in the percentage-based payment structure.
An hourly fee at least solves the problem that the percentage fee.
causes, but it causes an analogous problem with time. When a.
wedding planner (or any vendor) charges you by the hour, they.
lose their incentive to move fast, and you have very little.
control over this. Since you're not doing the work, it's tough.
for you to say exactly how long it should take. If you're.
working with a wedding planner who charges by the hour, set a.
maximum number (or range) of hours you'll pay for, while making.
sure that the planner agrees that the maximum you set is an.
adequate amount of time to plan your entire wedding.
Planners who charge a flat fee for each specific service they.
provide give you great flexibility. You don't have to hire them.
to plan every part of your wedding. , if you want them to handle.
the venue and catering, while you hire your cousin's band and.
have your mom make your dress, you have lots of flexibility in.
paying for just the services you need, but no others. By.
charging a flat fee per service, the planner maintains all normal.
( and desirable) goals to get the work done quickly and.
inexpensively. They don't get paid more for failing at one of.
those goals, as they do with the other payment methods.
Unfortunately, planners dislike this payment structure because.
they fear that there will be something unusually difficult about.
your wedding, and they'll have to eat the cost of dealing with.
it. Particularly wedding planners who are new to the field feel.
uncomfortable trying to predict ahead of time how much time and.
effort it will take to provide the services you require. If you.
propose the use of this payment structure to a wedding planner.
who normally charges differently, make it clear that you're aware.
of this concern and find it reasonable. Discuss the fact that.
If, you're willing to accept add-on charges (probably by the hour).
an unusual situation, beyond the planner's control, occurs. As.
with all types of wedding planners, be sure to ask to speak to.
references, and talk to these brides-who-have-gone-before-you.
about exactly what the wedding planner did and didn't do for each.
service she provided.
Just because a particular wedding planner.
usually charges clients a certain way, doesn't mean they can't.
get paid by another method. Most wedding planners are freelance.
agents, who can define their own rules for how they get paid.
Perhaps they've always charged percentages in the past, but that.
doesn't mean they couldn't agree to get paid a flat fee for.
specific services for your wedding, if that's the only way you're.
willing to pay. Of course you must be aware that this also means.
that they can walk away and not take you as a client, if they.
really don't want to accept the payment structure you're.
Negotiate with a wedding planner just as you would with any other.
vendor. Remember that you're hiring them. They are your hired.
help. If you don't like their terms, you can find a different.
wedding planner to contract with. You're the one holding all the.
cards. Play them.
Normal Hair Growth Cycles
No hair grows from the follicle for 90 days. Once this time has passed, a new hair begins growing through the skin and continues for another three to five years at a rate of approximately 1/2 inch per month.
It is thought that as many as 100 genes are involved in regulating the creation, construction and cycling of scalp hair. To date, very few of these genes have been identified.
Common Pattern Hair Loss
Hamilton-Norwood Hair Loss Scale
For those concerned about hair loss, many myths and half-truths abound, but useful information can be difficult to obtain. Therefore, an objective overview of pattern hair loss is presented herein.
In healthy well-nourished individuals of both genders, the most common form of hair loss is androgenetic alopecia (AGA), also known as pattern hair loss. The disorder affects approximately 40 million American men. Perhaps surprisingly, the same disorder affects about 20 million American women. The difference between women and men is that a woman suffering hair loss usually retains her feminine hairline and experiences thinning behind this leading edge. In men, a distinct "pattern" of loss manifests where the frontal edge recedes at the same time that a thinning zone expands from the posterior crown. In more pronounced cases, these zones meet and the person is said to be clinically bald.
Importantly, three things need to occur in order for one to be affected by AGA. Nine year old children do not experience pattern hair loss. And third, one needs to have the circulating hormones that precipitate onset and progression of the disorder.
Typically, the earliest onset of AGA occurs in late puberty or one's early 20's. As a general rule, the earlier hair loss begins, the more pronounced it is likely to become.
Hormones, Enzymes & Other Factors
Crystallography of DHT molecule
From a susceptibility standpoint, the principle hormonal trigger linked to pattern hair loss is 5-alpha dihydrotestosterone, commonly referred to as DHT. Intriguingly, it has been shown that in persons genetically insensitive to DHT, pattern hair loss does not occur. DHT is synthesized from the androgen hormone testosterone and is useful early in life and during puberty.
In adults, DHT is thought to cause significant harm, but very little good. Disorders as disparate as benign prostatic hyperplasia and pattern hair loss are both triggered by DHT. The synthesis of DHT occurs via two closely related forms of the enzyme 5-alpha reductase. Hair loss treatment options that efficiently interfere with the interaction between 5-alpha reductase and androgen hormones like testosterone have been shown to offer clinical benefit in treating pattern hair loss.
Because hair growth is regulated by multiple genes and attendant biochemical pathways, the underlying factors are extremely complex. Another challenge to understanding hair loss has been the fact that humans, alone among mammals, suffer from androgenetic alopecia. Thus, no efficient animal model exists that would otherwise tend to shed light upon the key factors at work.
Hair Loss Variations Other Than AGA
In either gender, the differential diagnosis is typically made based on the patient's history and clinical presentation. The common differentials for AGA include alopecia areata (AA), Trichotillomania, and telogen effluvium. Less often, the cause of hair loss may be associated with disorders such as lupus erythematosis, scabies or other skin manifesting disease processes. Scalp biopsy and lab assay may be useful in ascertaining a definitive diagnosis, but, in such cases, should generally only follow an initial clinical evaluation by a qualified treating physician.
Pattern Hair Loss Treatment Options
It has wryly been observed that the choices for dealing with hair loss are "drugs, plugs, or rugs". This quip articulates three treatment options that are more kindly referred to as non-surgical hair systems, surgical hair restoration, and pharmacotherapy. A fourth option has recently evolved, which will also be touched on herein. This is non-drug based therapy.
Typical Hair Piece
Hair replacement systems have been in regular use at least since the time of ancient Egypt. These products also go by the term hair integration systems, wigs, weaves, hair pieces, toupees and many other names.
Such attachment to the living scalp is almost never permanent, and for good reason. Aside from the fact that the unit itself wears out, basic hygiene dictates that the wearer regularly remove the unit to clean the underlying hair and scalp. There are almost always three basic elements to a hair replacement system. The first is the hair itself which may be synthetic, natural, or a combination thereof. The second element is the base of the unit. Typically, the hair is woven in to a fabric-like base which is then attached in some fashion to the scalp. This brings up the third element; which is the means of attachment. Methods include sewing the base to the fringe hair, gluing the base to the fringe hair, or gluing the base to the bald scalp.
Potential advantages to hair systems include the immediacy of achieving a full hair "look" that can appear, to the casual observer, to approximate a full head of hair. The potential disadvantages of hair systems are many and varied.
In persons who are actively losing hair, vs. those who are essentially bald, the hair system itself may rapidly accelerate the process of going bald. Another disadvantage is the hard leading edge that can give away the fact that a person is wearing a hair system. In the past, this problem has been addressed by using delicate lace front artificial hairlines that look quite natural but tend to be extremely fragile.
Because they are nonliving, hair systems must be serviced and eventually replaced themselves. The costs of servicing and maintaining a hair replacement system are not insubstantial-- and such costs can dramatically exceed the initial price of acquisition.
Surgical Hair Restoration
Surgical hair restoration, commonly known as hair transplantation, exploits a phenomenon first described in the 1950's. This phenomenon, donor dependence refers to the observation that hair bearing tissue, when relocated to a previously balding area of the same person's scalp, continues to produce viable, vigorously hair that persists in its new location as it otherwise would, had it not been "relocated". In appropriately selected patients, surgical hair restoration can constitute a positive solution to pattern hair loss
There are important caveats to hair transplantation. The first concerns supply and demand. At the present time, one may not transplant hair from one person to another without causing a destructive and florid foreign body response in the recipient. Thus, both operator and patient are relegated to whatever permanent hair bearing tissue is in place. Accordingly, it is highly important to conserve and strategically place this precious resource appropriately.
A hair line that is spotty or too abrupt may look worse than it did before it was restored. By the same token, hair behind the leading edge that is not restored in a fashion that yields meaningful density (e.g. 1 hair per mm/sq) often fails to approximate a full head of hair.
The third caveat to hair transplantation refers to a problem known as chasing a receding hair line. Because hair loss is relentless and progressive, it is possible that donor hair restored integrated into an apparently intact area of scalp hair may end up as an island of hair because the hair behind it continues to erode.
Ideally, for persons undergoing transplant surgery, it would be helpful to incorporate a treatment option that safely and effectively arrested the progression of hair loss, allowing the treating surgeon to fill in the thin areas without the concern of chasing a receding hair line.
Drug-based Hair Loss Treatment Options
From a treatment perspective, the two most widely used therapeutic interventions against pattern hair loss have been topical minoxidil and oral finasteride.
Minoxidil, first sold under the trade-name Rogaine( TM) was initially developed as the oral antihypertensive drug, Loniten( TM). In some patients who used minoxidil to treat blood pressure problems, it was observed that unusual hair growth occurred on the face and scalp. Rogaine( TM) (2% minoxidil) was the first hair loss treatment drug approved by the FDA for use in men.
The advantages of Rogaine( TM) include the ability to arrest, and possibly reverse, pattern hair loss. Based on Pfizer's own marketing materials, Rogaine( TM) has primarily been shown to be effective in treating hair loss in the vertex and posterior scalp, but not the anterior hairline. Minoxidil is a potent drug with potential side effects that include hypotension and skin irritation.
Finasteride, a selective type II 5-alpha reductase inhibitor was originally developed, in 5 mg oral dosage, under the trade name Proscar( TM) to treat benign prostatic hyperplasia (BPH). Because BPH is linked biochemically to the same metabolic pathways that trigger pattern hair loss, it was hypothesized that finasteride could be clinically useful in both pathologies. From this work, Propecia( TM) (1 mg finasteride) was developed. In placebo-controlled studies on men with mild to moderate hair loss, Propecia( TM) was shown to produce clinically relevant benefit in arresting, and in some cases, reversing the progression of the disorder. Propecia( TM) is not indicated for use in women. Noted side effects include reduced libido, as well as reduced ejaculate volume. Gynecomastia (male breast enlargement) is another potential side effect. Finasteride can also artificially lower the levels of a key protein (PSA) used to screen for prostate cancer. Finasteride is considered a teratogen (may cause feminizing birth defects) and should not be handled by pregnant women or even those persons who may come into contact with pregnant women.
Like finasteride, dutasteride was originally developed to treat BPH. Unlike finasteride however, dutasteride inhibits both click here isoforms of 5-alpha reductase, while finasteride inhibits only type II 5-alpha reductase. Interestingly, a clinical study undertaken by GlaxoSmithKline, the EPICS trial, did not find dutasteride to be more effective than finasteride in treating BPH.
At the present time, dutasteride is approved to treat BPH. Clinical trials for dutasteride as a hair loss drug were undertaken, but halted in late 2002. Potential side effects noted with the use of dutasteride include gynecomastia, changes to PSA levels, teratogenic effects and others that closely parallel the negative side effect profile described by the makers of finasteride.
In December 2006, GlaxoSmithKline embarked on a new Phase III, six month study in Korea to test the safety, tolerability and effectiveness of a once-daily dose of dutasteride (0.5 mg) for the treatment of AGA in the vertex region of the scalp (types IIIv, IV and V on the Hamilton-Norwood scale). The future impact that this study will have on the FDA's approval or disapproval of Avodart for the treatment of male pattern baldness in the United States is yet to be determined.
On occasion, but specifically in female patients drugs including spironalactone & flutamide have, on occasion been used off-label to treat various forms of hair loss. Each drug comes with a host of potential side effects, and none has been approved by the FDA for the treatment of pattern hair loss.
Non-drug based Hair Loss Treatment Options
Recently, botanically derived substances have come under serious investigation as potentially useful tools against AGA. This effort has been largely pioneered by the makers of HairGenesis(TM). After the creation of HairGenesis(TM) a number of other products came on the market. Some incorporated drugs like minoxidil. Others, used variations on the theme of non-drug based formulations. However, aside from HairGenesis(TM), none has been supported with a third party, IRB monitored, placebo-controlled, double blind study-- published in the peer-reviewed medical literature. This makes HairGenesis(TM) unique in the category. For those wishing to see how HairGenesis(TM) is thought to compare to other hair loss treatment options, a review of the HairGenesis(TM) Comparison Page is encouraged.
Inasmuch as the bulk of this website focuses on the benefits associated with HairGenesis(TM), the numerous points in favor of HairGenesis(TM) treatment will not be reiterated herein. Two points are relevant to the present discussion, however, and will be concisely articulated.
The complex of naturally derived active substances used in HairGenesis(TM) have been shown to operate through pathways and mechanisms that are unique from one another, as well as separate and apart from those within which drug-based treatments work. Suffice to say that this observation has presented a unique opportunity to develop HairGenesis into a "cocktail" treatment wherein formulation synergy would most likely occur.
In plain English, this means that HairGenesis(TM) has been designed to be greater than the sum of its parts.
In healthy well-nourished individuals of both genders, the most common form of hair loss is androgenetic alopecia (AGA), also known as pattern hair loss. These products also go by the term hair integration systems, wigs, weaves, hair pieces, toupees and many other names. Surgical hair restoration, commonly known as hair transplantation, exploits a phenomenon first described in the 1950's. By the same token, hair behind the leading edge that is not restored in a fashion that yields meaningful density (e.g. 1 hair per mm/sq) often fails to approximate a full head of hair. Because hair loss is progressive and relentless, it is possible that donor hair restored integrated into an apparently intact area of scalp hair may end up as an island of hair because the hair behind it continues to erode.